Research activities on the GGC Partnership Campus span a variety of biomedical applications using diverse methodologies –

all with the singular purpose of better understanding human disease to guide the development of solutions that improve the quality of life for patients.

Model Organisms 

Greenwood Genetic Center’s Allin Aquaculture Facility is a state-of-the-art zebrafish laboratory advancing the understanding of a variety of rare disease including lysosomal storage disorders and congenital disorders of glycosylation. Greenwood Genetic Center’s Functional Studies Unit helps clarify patient variants and works to identify potential treatments for rare diseases.

Clemson Center for Human Genetics utilizes the fruit fly, Drosophila melanogaster, a classic model for large scale genetic studies. Faculty integrate high-throughput genome sequencing technologies and analyses of large data sets with advanced computational approaches to acquire broad-based insights in the composition and dynamics of genetic networks that are associated with variation in complex traits in human health and disease. Collaborative efforts with the Greenwood Genetic Center expand studies to include zebrafish models, as well as studies on human cell lines and patient samples.

Diagnostic Testing

With the Greenwood Genetic Center’s four decades of experience in diagnostic testing, the laboratories are constantly innovating using state-of-the-art technologies for clinical patient care. In collaboration with the Clemson Center for Human Genetics, GGC houses the only NovaSeq 6000 sequencing instrument in South Carolina providing both clinical exome and genome sequencing technology for diagnostic as well as research applications.

The Greenwood Genetic Center’s collaboration with Circa Bioscience is advancing the identification of biomarkers for a variety of common and rare disorders. In addition, national and international industry partners are working with GGC’s Diagnostic Laboratories to identify patients, develop improved treatments, and monitor treatment efficacy for a variety of metabolic disorders.